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Foretinib simultaneously inhibits cancer cells and lymphatic endothelial cells to reduce pancreatic tumor growth in vivo , and this data demonstrated for the first time that this inhibitor suppresses angiogenesis and lymphangiogenesis by blocking VEGFR-2/3 and TIE-2 signaling [77]

gondii lysate antigen or its antigenic component, Toxoplasma lysate-Ig8 also demonstrated significant inhibition of tumor growth induced by 20-methylcholanthren in the murine models [226228] and induced cytotoxic activity on the YAC-1 murine lymphoma cell line [226]

Bioenergetic profiling The real-time OCR was measured using a Seahorse Mini HS XF instrument (Agilent)

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