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Reconstitution Steps Remove the vial from freezer storage (20 C / 4 F) and let it equilibrate at room temperature for 1520 minutes

Furthermore, the incidence of grade 3 or higher TRAEs was 25.6% among those who received dato-DXd vs 42.1% in patients who received paclitaxel in TROPION-Lung01

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Nature Communications

Those steps are part of the clinical training a provider delivers to a patient who has already been evaluated and prescribed a compound, not a public how-to for anyone with a search bar