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The small molecule inhibitors or gene silencing of GLS1 expression has shown antitumor activity in a variety of cancers, including melanoma (Varghese et al., 2021), breast cancer (Gross et al., 2014), pancreatic cancer (Son et al., 2013), acute myeloid leukemia (Emadi et al., 2014), and malignant glioma (Yamashita et al., 2021)

However, the relatively large rTPJ VOI employed in our study constrains our capability to evaluate the specific functional roles of these subdivisions

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Areti et al., Regarding to CIPN induced by the taxanes, Duggett et al

It is an immune modulator that enhances regulatory pathways (Tregs, tolerogenic dendritic cells) more than effector pathways

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