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Nitric oxide modulation: Balances inflammation and enhances vascular tone

A history of cancer or active malignancy is frequently flagged in the literature as a reason for caution, because pathways involved in angiogenesis and cell migration are also relevant to tumor biology

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Since Provenge (sipuleucel-T) was approved by the FDA as the first cancer vaccine for prostate cancer, peptide vaccine therapy has been widely used for other cancers, including gastric, colorectal, and pancreatic [162]

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