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In Phase III, products of phases I and/or II are excreted from cells by multidrug resistance proteins and other ABC transporters [37]

Slides were viewed and imaged using a Leica TCS SP5-X inverted confocal microscope (Leica Microsystems, Buffalo Grove, IL)

Another study showed that DFO could suppress excessive collagenase-mediated type II collagen cleavage and protease, production of cytokine, and COL10A1 expression while upregulating adenosine monophosphate-activated protein kinase and Krebs cycle genes in human osteoarthritic cartilage [125]

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