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While constipation is a common side effect, Bowel Obstruction or Ileus (where the gut stops moving entirely) is a rare but serious medical emergency associated with GLP-1 use

IV dosing may be appropriate in cases of severe deficiency or for individuals who require rapid correction of vitamin levels

Despite a recommended daily intake as low as 6 micrograms, B12 deficiency remains common, particularly among individuals following vegan or vegetarian diets

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To avoid AMP degradation engineered probiotic bacteria (lactic acid bacteria-LAB) that colonize the human intestinal tract were tested as a delivery vehicle

The same applies if your elevated B12 is accompanied by abnormal results on other labs (liver enzymes, kidney markers, CBC), or by symptoms like unexplained weight loss, persistent fatigue, abdominal pain, or easy bruising