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First-in-human (FIH) clinical trials are the initial Phase 1 studies and thus pose significant challenges regarding their design and safety

Batch identification labeling supports traceability and internal documentation within research environments

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Direct effects on cellular proliferation A genetically engineered murine model of pancreatic intraepithelial neoplasia (PanIN) to PDAC progression ( LSL-Kras G12D ;Pdx1-Cre, KC ) treated with exenatide demonstrated architectural changes of loss of polarity and micropapillary formation following 12 weeks of therapy 18

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For reference, the control condition (1 M cisplatin without BBB, just the PET membrane) showed 46.68 10.35% viability, confirming the drugs cytotoxic potential (Fig