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The pathophysiological mechanisms linking this persistence to post-COVID IBS likely involve: Sustained inflammatory responses with elevated interferon levels Expansion of activated immune cells even 8 months post-infection Intestinal dysbiosis affecting the gut-brain axis Increased intestinal permeability during and after infection These findings suggest that long-term GI symptoms after COVID-19 may stem from ongoing intestinal inflammation driven by viral persistence, rather than merely representing psychological sequelae of the acute illness

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10.1080/08923973.2016.1274997 40 RaineT.BonovasS.BurischJ.KucharzikT.AdaminaM.AnneseV.et al (2022)

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First, antioxidant properties allow alpha-lipoic acid to neutralize free radicals and reduce oxidative stress, which is linked to damage that can increase heart disease risk ( Second, its been shown to improve endothelial dysfunction a condition in which blood vessels cannot dilate properly, which also raises the risks of heart attack and stroke ( Whats more, a review of studies found that taking an alpha-lipoic acid supplement lowered triglyceride and LDL (bad) cholesterol levels in adults with metabolic disease ( Summary Alpha-lipoic acid has strong antioxidant properties, which may reduce inflammation and skin aging, promote healthy nerve function, lower heart disease risk factors, and slow the progression of memory loss disorders