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The main adverse events were erythrodysesthesia, hypertension, increased aspartate aminotransferase level, fatigue, and diarrhea

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Demographics Known risk factors and demographics for neuropathic pains include female sex, younger age, higher BMI, smoking history, manual or personal service occupations, lower socioeconomic status, and ethnic minority status, along with medical conditions such as diabetes, peripheral neuropathy, musculoskeletal disorders (such as rheumatoid arthritis, osteoarthritis, and fibromyalgia)

It offers absolute quantification but requires sacrifice of multiple animals