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74 The pathophysiology of APAP-induced liver injury involves a complex interplay of cellular events, with inflammasome activation emerging as a critical component of the inflammatory response

,, Although there are several inhibitors of the cystine/glutamate transporter other than sulfasalazine, these drugs have limitations of low bioavailability and low selectivity to of the cystine/glutamate transporter in vivo

Immune cell circulating subsets are affected by gonadal function

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Death from hepatic injury usually occurs 35 days post-ingestion

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