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Bacteria or their components (such as LPS and bacterial DNA) originating from the oral cavity may serve as PAMPs upon migrating to the gut, directly activating inflammasomes in intestinal epithelial cells or immune cells, thereby becoming key ligands for inflammasome activation

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Figure 1: Changes in percentage of weight lost across all experimental treatment groups

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It is therefore important for psychiatrists to consider this diagnosis when evaluating psychiatric symptoms, especially if the patient has a history of liver disease