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Due to the large absorptive area and a rich vascular supply, the orobuccal mucosa allows a rapid absorption of glutathione and other substances by passive transport through or around the cells into the abundant capillary circulation

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Additionally, Glutathione is essential in a broad range of metabolic processes: Glutathione acts to neutralize a toxic metabolic byproduct: Methylglyoxal

Glutathione supplementation has also been suggested as a promising treatment to combat the oxidative stress found in people with HIV

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