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Subgroup analyses were performed according to GSH dose

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Physiol Rev 75(3):519560 Krishnan L et al (2003) Effects of angiogenesis on the material properties of the extracellular matrix: correlation with gene expression

Week 12: Detox begins, skin feels cleaner but no visible change Week 34: Slight glow and softness in skin tone Week 56: Pigmentation begins to reduce slightly Week 710: Noticeable brightness, improved skin tone Week 1016: Significant skin lightening for most skin types Week 16+: Best results for medium to deep complexions FAQs: 1

By integrating mechanistic and pharmacological insights, this work aims to establish a comprehensive theoretical framework for advancing SIRT1-based therapeutic strategies in MASLD