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iScience 28, 113265

Histone methyltransferase Suv39h1 regulates hepatic stellate cell activation and is targetable in liver fibrosis

However, given that previous demonstrations of longevity resulting from disruption of this pathway occurred either at conception or in young adulthood 6,7,17,18,19 , along with the reported importance of low exposure to GH (and IGF-1) signals early in life on longevity and related outcomes 20,21 , whether benefits can be achieved by targeting this pathway later in life is unclear

The peptide may prove most valuable as an adjunct to post-surgical rehabilitation or for managing small, stable tears conservatively

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