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Human studies will help to further elucidate its therapeutic potential.

However, a discovery that bacterial pore-forming toxins can induce necroptosis (a programmed necrosis) also in red blood cells (RBCs) is striking and could eventually lead to a re-conception of erythrocytes as entities between life and death [25]

A systematic review and meta-analysis of the effects of Hibiscus sabdariffa on blood pressure and cardiometabolic markers

Shareena Dasari et al

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Limitations of current studies When considering the limitations, not all studies used the same level of microscopic assessment, however, this is to be expected