It sits well under the ~500 Da Lipinski cutoff for good oral absorption, so absorption is built into the chemistry
2.2 Dosage Information The recommended daily dosage volume of 1.5 mL, 3.25 mL, or 5 mL of the reconstituted solution is based on the patient's actual weight of less than 1 kg, 1 kg to less than 3 kg, and more than or equal to 3 kg, respectively (see Table 1)
Common reconstitution scenarios clinicians use: 50 mg vial + 2.5 ml water 20 mg/ml - 1 mg = 0.05 ml ( 5 units on a U-100 insulin syringe)
It activates fibroblasts and increases nitric oxide production to stimulate vascular and connective tissue regeneration [9, 10]
Serious reactions are rare and almost always fixable when caught early
This is the common, diagnosed cause of B12 deficiency in the UK