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Caries are typically caused by acid-producing bacteria, such as Streptococcus and Lactobacillus , which ferment carbohydrates and create a low-pH environment within dental biofilms, leading to tooth demineralization 31,32

Biol Trace Elem Res 202:39994006

The development of phyto-nanoformulations addresses these issues by improving the bioavailability and targeted delivery of plant-derived compounds

Alexandrova, A

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Serotonin is a regulator of numerous physiological activities, including behavior, mood, memory, neurogenesis, embryonic development, smooth muscle homeostasis, liver homeostasis, and gastrointestinal homeostasis 17,18,19