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5-amino-1MQ has a 46 hour half-life requiring daily administration to sustain NNMT inhibition

This process engages a coordinated network of regulated cell death that extends beyond ferroptosis to include crosstalk with necroptosis and pyroptosis, while being critically modulated by ferritinophagy and the paradoxical role of defective mitophagy

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Long-term metformin therapy and vitamin B 12 deficiency: an association to bear in mind