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In people who have difficulty absorbing vitamin B12 from food, vitamin B12 injections or nasal spray may be necessary

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doi: 10.1007/s11596-018-1862-9

For more detailed scientific research on B12, the National Institutes of Health offers excellent resources

This has led to a proliferation of private clinics and practitioners offering so-called booster shots of B12 as a pick-me-up to help decrease fatigue, improve mood, motivation, and provide a feeling of being refreshed even in those without a diagnosed deficiency, also targeting vegans and vegetarians as a cohort at risk of B12 deficiency