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To recapitulate the cellular phenotypes of GDH1 knockdown, we first excluded RBPs whose knockdown resulted in apparent growth arrest and cell death ( HuRNPC and RBM8A ) (Extended Data Fig

Insect GSTs not only are involved in xenobiotic conjugation but also play roles in protection against oxidative stress caused by exposure to pesticides [46], plant allelochemicals [54], as well as various other abiotic factors [55, 56]

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Thus, disturbances in mitochondrial ICS biosynthesis could contribute to failures in the supply of energy (which might result in cell death) or to cancer, since genomic instability is considered as a hallmark of cancer and a driver of neoplastic transformation processes

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