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Epithalon represents a distinct longevity-research angle from NAD+: where NAD+ concerns cellular energy and sirtuin signaling, Epithalon concerns chromosomal aging and the telomere-maintenance machinery

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Carcinogenesis 29:102232 Natarajan VT, Singh A, Kumar AA (2010) Transcriptional upregulation of Nrf2-dependent phase II detoxification genes in the involved epidermis of vitiligo vulgaris

Food Chem 89(3):403409 Puttaraju N, Venkateshaiah SU, Dharmesh SM, Urs SMN, Somasundaram R (2006) Antioxidant activity of indigenous edible mushrooms

This can lead to inflammation and "follicle miniaturization," where the hair grows back thinner and shorter with each cycle