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Interestingly, U11, U12, and U13 were induced by all treatments except in cat2 and cat2 gr1 (Figure 4, compare A and B with C and D)

EAAT2 prevents excitotoxicity by maintaining extracellular glutamate concentrations at ~25 nM [308, 370373]

Lifestyle changes for MCAS: Low-histamine Diet: Allergy elimination diets and low-histamine diets have been shown in studies to be helpful to some people with chronic itching (one symptom of MCAS)

So it's not something that's not doable