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10.1016/j.pnpbp.2023.110915 16 KapsiS.KatsantoniS.DrigasA

Patti M, Christian R, Palokas M

Researchers value the predictable construction and ease of handling offered by this format, which helps reduce variability across samples and supports reliable documentation during long-term research projects

The compounds demonstrated different pharmacology in vivo, with TLC-2716 having lower plasma exposures and higher and sustained ileum and liver exposures (due to active uptake into hepatocytes) than TLC-6665 (ratio of AUCs of TLC-2716/TLC-6665 in plasma and liver of 0.17 and 6.24, respectively

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