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A suitable section of the skin was cut and fitted between the donor and receptor slots of an upright Franz diffusion cell (FDC) (Logan Diffusion Cells, USA), with the stratum corneum faced toward the donor chamber (where the formulation was putted on) and the dermis fronting the receptor compartment

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Diabetes Care 2005;28:1068-76

Selank Mechanism: Modulates GABA and serotonin pathways, influencing anxiety and mood

Additionally, uricase can cause gastrointestinal discomfort, including nausea and vomiting, leukopenia, hair loss, and other adverse reactions