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These studies have revealed that adolescent THC exposure induces core schizophrenia-related endophenotypes resembling positive and negative symptoms, such asocial motivation deficits, affective dysregulation, cognitive and sensorimotor gating abnormalities [4, 5]

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These two characteristics make it inherently unsuitable for standard topical delivery: it degrades before it absorbs, and it repels the lipid-rich skin barrier

Immunocytochemistry Cells grown on coverslips were fixed (4% paraformaldehyde), permeabilized (0.2% triton), and stained by immunofluorescence

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The reconstituted solution remains stable for approximately 30 days under proper refrigeration