After reviewing literature and conducting a two-round Delphi survey with 42 experts, a consensus emerged that emphasizes prioritizing clinical symptoms in diagnosis, with serum B12 as a screening marker supported by methylmalonic acid or homocysteine levels for additional confirmation
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Typically, people with vitamin 12 deficiency may develop skin darkening on the hands, feet, gums, and tongue
A 2020 study found that the death rate among people with the highest levels of B12 in their bodies was almost twice as high as that of people with the lowest levels of B12
The liberation of FA from TAG by adipocyte lipolysis is also important to supply substrate for hepatic synthesis of very-low-density lipoproteins (VLDLs)
