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P values were derived from two-sided unpaired t-test ( b ), two-sided Pearsons chi-square tests ( f ), One-way ANOVA ( c,d,g,h,j,i )

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This observation of higher calcium influx in BD is intriguing in the context of iron overload since calcium and iron have a bidirectional relationship where high Ca +2 influx causes increased LIP and iron overload promotes massive Ca +2 influx [145, 146]

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