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Furthermore, macrophages from aged individuals exhibit impaired mitophagy, the process of recycling damaged mitochondria

[PubMed: 9814446] 209

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however, in later stages SJS/TEN can be distinguished from EM: established SJS/TEN shows full-thickness keratinocyte necrosis that develops into subepidermal bullae vs

12 , e494e503 (2011)