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They are phagocytosed by macrophages as foreign particles and recognized by Toll-like receptors 2 and 4 (TLR2/TLR4), which subsequently activate and oligomerize the NLRP3 complex

Las interacciones hormonales requieren monitoreo cuidadoso en algunas pacientes femeninas

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The downregulation of SLC7A11, a component of system Xc-, results in diminished GSH production and GPX4 activity, hence increasing chondrocyte vulnerability to ferroptosis [92,93]

It acts as a chemoattractant, recruiting immune cells like macrophages and mast cells to the site of investigation