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Genome-wide CRISPR-Cas9 knockout screening The Brunello CRISPR knockout pooled library 18 , which contains 76,441 single guide RNAs (sgRNAs) targeting 19,114 genes in the human genome, was used for genome-wide loss-of-function screening

Passive targeting of tumors relies on the EPR effect in leaky tumor blood vessels, which allows nanoparticles to enter and remain in the tumor interstitial sites [81]

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Different in vitro proliferation and cytokine-production inhibition of memory T-cell subsets after calcineurin and mammalian target of rapamycin inhibitors treatment

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