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(Pececnik et al., 2025) These are genuinely interesting mechanistic observations

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It was discovered more than 60 years ago that tumor cells had a unique capacity to display reduced rates of respiration, which typically cause the death of healthy cells, together with increased glycolysis and pentose phosphate cycle activity ( Figure 2 )

As a key stress signal, ROS oxidizes the mitochondrial outer membrane protein Tom20, altering its structure and enhancing its ability to recruit Bax

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Verga JU, Padovano C, Da Silveira WA, Hazard ES, Nugent AP, Elliott CT, Carnevali O, Galeazzi R, Hardiman G (2024) A systems biology approach reveals the endocrine disrupting potential of aflatoxin B1