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Publishing in Nature Genetics, a research team led by the department of Gene Technology at KTH Royal Institute of Technology published a detailed map of the developing human heart, showing how different groups of cells are arranged and how they interact in fetal heart development

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When gain-of-function LRRK2 mutants are anchored to mitochondria, it phosphorylates and traps Rab10 nearby (Gomez et al., 2019), causing decreased interaction of Rab10 with OPTN (optineurin), which is an autophagy receptor, therefore impairing mitophagy (Wauters et al., 2020)