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As with doxorubicin, cisplatin treatment also results in ROS generation, which is neutralised by the NADPH-powered glutathione system, warranting investigation of this strategy for other forms of chemotherapy which are detoxified via this system

In addition, knockdown of GLUD1 in cancer cells decreased the NADPH/NADP + and GSH levels

In patients with T2D, GLP-1RA were associated with a 21% reduction in composite kidney outcomes mostly driven by amelioration of albuminuria 80

However, when used as part of a comprehensive health routine, it may support recovery and contribute to overall health and wellness as a dietary supplement