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Primary Human Hepatocytes (PHHs) are considered the gold standard of vitro models for predicting in vivo metabolism because they can mimic hepatic metabolic reactions, including those catalyzed by cytochrome P450 (CYP) enzymes and by flavin-containing monooxygenases (FMOs), as well as conjugation with glucuronic acid, sulfate, and glutathione to a large extent

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Identification of transferrin receptor 1 as a hepatitis C virus entry factor

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The study found that those who received Liraglutide lost significantly more weight compared to the placebo group

Deregulated FASN expression in BRAF inhibitor-resistant melanoma cells unveils new targets for drug combinations