Important chemical contaminants reported to cause neurotoxic effects in humans at environmentally relevant levels of exposure include polychlorinated biphenyls (Schantz et al., 2003), arsenic (Wasserman et al., 2004), lead (Lanphear et al., 2005), manganese (Takser et al., 2003), pesticides (Rauh et al., 2006), polycyclic aromatic hydrocarbons (Perera et al., 2006) and mercury compounds (Grandjean et al., 1997
Brain Res 1649:151157
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In mouse murine pro-lymphoid (BaF3) cells with mutated JAK2 displayed significantly enhanced glutaminase metabolism and increased expression of GLS compared to wild-type cells [107]
[DOI] [PubMed] [Google Scholar] 20.Nawarskas J.J
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