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These results provide evidence for local alterations where mast cells contribute to the initiation of inflammatory arthritis and may be targeted in intervention strategies

In cartilage research, a 2015 study in a collagenase-induced knee osteoarthritis rabbit model showed that combined AOD-9604 and hyaluronic acid injections were significantly more effective than either treatment alone, with treated groups showing lower gross morphological and histopathological scores

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Its essential for the upkeep of various organ systems, cellular metabolism, and brain functions, plays a critical role in energy metabolism, immune function, and nerve health

doi: 10.1111/j.1572-0241.2008.02030.x