No wash steps, no specialized instrumentation Scalable to 384-well HTS format ELISA-quality data in a fraction of the time Is my compound activating immune cells
Oct 2013;111:128-35
Glutathione removes peroxides from membrane lipids and serves as a substrate for H 2 O 2 reduction to H 2 O via the action of glutathione peroxidase
Notably, whereas somatostatin gene knockout mice display increased glucagon and insulin release in response to nutrient stimuli compared with control mice, they show similar growth curves, islet sizes, hormone contents, resting normoglycemia and insulin sensitivity 7,11
Our findings show the effect of depletion of existing intracellular GSH and inhibition of GSH biosynthesis with a BSO-based peptide derivative, which provides a new strategy for in situ construction of selective and efficient nanomedicine for intracellular GSH regulation and tumor inhibition
Ageing Research Reviews, 2005