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Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities
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Patients were categorized into good (ASITN/SIR 34) and poor (ASITN/SIR 02) collateral groups
In preclinical adipocyte models, studies suggest this shift in metabolic flux is associated with changes in lipogenic gene expression, including reduced expression of key adipogenic transcription factors
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Reasons include: Poor gut absorption Chronic inflammation Long-standing deficiencies Stress-related nutrient depletion Lifestyle-induced hormonal imbalances This is where functional medicine becomes crucial
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