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Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis

Histology-confirmed features of necrotizing granulomatous vasculitis facilitate a diagnosis of granulomatosis polyangiitis, which is frequently associated with c- ANCA and proteinase- 3 antibodies

Consistent with P300, in vitro lactylation assays further substantiated the delactylase activity of SIRT1 (Supplementary Fig

Structural features of Cagri-bound active CTR complexes Previous structural analysis of CTR-Gs bound to rAmy revealed that the receptor complex was dynamic, adopting distinct states where the receptor was resolved into two major conformations, a bypass (55%, PDB: 7TYL) and CT-like (45%, PDB: 7TYI) conformation 15

This approach may allow for rapid differentiation of stereoisomers on a mass spectrometer