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In many bacteria, the reactions of the -oxidation cycle can be carried out by multiple proteins (FadA to FadM), with FadE as the acyl-CoA dehydrogenase, FadB as the dual enoyl-CoA hydratase and 3-hydroxylacyl-CoA dehydrogenase, and FadA as the 3-ketoacyl-CoA thiolase (see Fig 1

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Given this finding, those people regularly taking drugs with known hepatotoxicity (toxic to the liver) may benefit from consuming gamma-glutamylcysteine (GGC) that can help avoid chronic depletion of glutathione (GSH)

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Regulation of Human Class I Alcohol Dehydrogenases by Bile Acids. Journal of Lipid Research, vol