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demonstrated that in T cells with deficient mitochondrial transcription factor A genes ( Tfam ), mtDNA content decreased, leading to mitochondrial dysfunction

Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions

Once GSH is depleted, ROS and reactive nitrogen species escalate, leading to increased oxidative stress, mitochondrial dysfunction, and DNA damage

doi: 10.1016/s0015-0282(02)03105-9

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Then, without warning, he will nervously search for a cigarette, abandon his search in the middle of it (wise, since English cigarettes are bad), and seize his head in his two hands, twisting it from side to side and lowering his head near the board so the he can have a convenient recepticle if ever his head does come off