Importantly, the process does not involve the CYP450 enzyme system, showing no inhibitory or inductive effect on clinically significant isoforms such as CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP2E1, or CYP3A4
Lactate is a byproduct of anaerobic respiration, which is much less efficient compared to aerobic respiration
E.ParnetP.SonodaG.TestaJ
Yager et al
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