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Common Causes of "Leaky Gut" Multiple factors can contribute to increased intestinal permeability, and while scientific research continues to explore the full extent of these connections, the following are commonly recognized triggers: Diet especially when its high in processed foods, refined sugars, and artificial additives and preservatives, can disrupt gut microbiota and weaken the intestinal barrier

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14,16 Bromelain enhances quercetin absorption and has independent effects that support a healthy inflammatory response