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Same results were obtained on culture models, the P e values of ibuprofen were 0.28 and 0.53 10 6 cm/s across a porcine brain endothelial cell line and a rat primary brain endothelial based BBB models, respectively [71]

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77,78 Surprisingly, previous studies have confirmed the protective effect of smoking on UC, but it has likewise been suggested that active smoking can increase the incidence of adverse effects in the treatment of UC patients

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