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showed that the extent of PAGs inhibitory activity toward CSE, with cysteine as the substrate, depends on the preincubation time of the inhibitor with the enzyme as well as on the concentration of cysteine (Yadav et al., 2019)

N-Acetylcysteine used to be recommended because it may protect cells from oxidative stress

Taken together, our results reveal a hitherto unrecognized mechanism of ferroptosis defense by glycolytic LDHB and suggest a new strategy for the treatment of KRAS -dependent lung cancer

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For example, the regulation of HPV16 E7 by miR-27b enhances the proliferation and invasion of cervical cancer cells (Zhang et al., 2015)