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5), and by inference, neurotoxic damage.53 Forgione and colleagues had previously hypothesized that GPX1 deficiency directly induces an increase in vascular oxidative stress, with attendant endothelial dysfunction.54 Glutathione peroxidases, particularly GPx1 have also been implicated in the development and prevention of many common and complex diseases, including cancer and cardiovascular disease (Fig

Although it is clear that 5mC is altered in AD, there remains no clear conclusion about global DNA methylation changes in the AD brain

Additionally, it is also used in the treatment of cyanide poisoning, a condition that can cause rapid breathing, confusion, and seizures

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