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doi: 10.3109/17482960903278485 41 CapanniC.MessoriL.OrioliP.ChitiF.StefaniM.RamponiG.et al

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In chronic kidney disease, for example, studies describe a pro-oxidant state driven in part by reduced glutathione and glutathione peroxidase activity meaning the bodys antioxidant defenses are depleted exactly when theyre needed most