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They also generate reactive oxygen species during normal metabolism

Polymorphisms in the SOD3 gene have been linked to type 2 diabetes, ischemic heart disease, acute lung injury and COPD

To further characterize compound engagement of TGR in ex vivo worms using an orthogonal assay, inhibition of TGR activity in newly transformed schistosomula (NTS, skin-stage worms) was assessed using a TrxR-selective fluorescent probe 43,44 , TRFS-Green

In the body, O 2 - anions are intended products of redox signaling enzyme cascade and byproducts of several metabolic processes including mitochondrial respiration 555

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