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Interestingly, previous transcriptional analysis uncovered that AITC treatment affected the expression profile of certain genes involved in the regulation of cell cycle 23 , indicating the phytochemical-induced growth inhibition might be an indirect consequence of cell cycle misregulation due to GSH depletion

Early mitochondrial calcium defects in Huntingtons disease are a direct effect of polyglutamines

This redox imbalance promotes enhanced expression of T2-associated proteins, leaving the cells vulnerable to oxidatively induced cell death and, potentially, to asthma exacerbations

Clinical and genetic predictors of paclitaxel neurotoxicity based on patient- versus clinician-reported incidence and severity of neurotoxicity in the ICON7 trial

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