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Hsp60, Hsp70, and gp96 can enhance the expression of B7 and MHC-II on the surface of plasmacytoid dendritic cells (antigen presenting cells), stimulate dendritic cell maturation, migration to draining lymph nodes, and induce the secretion of chemokines by macrophages and plasmacytoid dendritic cells (DCs) (36)

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In many human cancer cells, the KEAP1-mediated regulation of NRF2 activity is abrogated, resulting in the persistent activation of NRF2

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This overload activates autophagy pathways, disrupts cellular homeostasis, and induces mitochondrial damage, ultimately synergizing with GO-based PTT for effective oral cancer cell destruction (Lv et al

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